Seyed Mahmoud Arab Najafi

Journal Paper

1. "The effect of Psilocybe cubensis alkaloids on depressive-like behavior in mice exposed to maternal separation with respect to hippocampal gene expression and DNA methylation of Slc6a4 and Nr3c1"
   Eghbal Jasemi, Ali Razmi, Salar Vaseghi, Shayan Amiri, Seyed Mahmoud Arab Najafi
   BEHAVIOURAL PHARMACOLOGY, Vol. 36, pp.115-126, 2025
2. "Synergic anti-tumor effects of photodynamic therapy and resveratrol on triple-negative breast cancer cells"
   Masta Ghazizadeh, Khatereh Khorsandi, Seyed Mahmoud Arab Najafi
   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, Vol. 24, No 3, pp.451-465, 2025
3. "Lentiviral Delivery System: A Revolutionary Approach in Gene Therapy"
   Fatemeh Eslamizadeh, Ehsan Farashahi Yazd, Seyed Mahmoud Arab Najafi
   Regenerative Biomedicine, Vol. 1, No 1, pp.12-16, 2024
4. "The Role of miR-29a and miR-143 on the Anti-apoptotic MCL-1/cIAP-2 Genes Expression in EGFR Mutated Non-small Cell Lung Carcinoma Patients"
   Zahra Abrehdari-tafreshi, Ehsan Arefian, Nasser Rakhshani, Seyed Mahmoud Arab Najafi
   BIOCHEMICAL GENETICS, Vol. 62, No 6, pp.4929-4951, 2024
5. "Regulation of Wnt Signaling by Heterotrimeric G-Proteins"
   Seyed Mahmoud Arab Najafi
   Asian Journal of Biology, Vol. 19, No 4, pp.59-73, 2023
6. "Gαq Signaling Activates β-Catenin-dependent gene transcription"
   SARA ANSARI, Sedighe Kolivand, SARA SALMANIAN, Marie Saghaeian Jazi, Seyed Mahmoud Arab Najafi
   IRANIAN BIOMEDICAL JOURNAL, Vol. 27, No 4, pp.183-190, 2023
7. "Inhibitors of Gq signalling down-regulate β-catenin expression & function in human colon cancer cells"
   Nasim Forghani, Seyed Mahmoud Arab Najafi
   INDIAN JOURNAL OF MEDICAL RESEARCH, Vol. 154, No 6, pp.833-842, 2021
8. "Membrane Localization of β-Catenin in Prostate Cancer PC3 Cells Treated with Teucrium persicum Boiss. Extract"
   Narges Barati, مجید تفریحی , Seyed Mahmoud Arab Najafi
   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, Vol. 73, pp.1-10, 2021
9. "The Canonical Wnt Signaling (Wnt/β-Catenin Pathway): A Potential Target for Cancer Prevention and Therapy"
   Seyed Mahmoud Arab Najafi
   IRANIAN BIOMEDICAL JOURNAL, Vol. 24, No 5, 2019
10. "Beta‑catenin Forms Protein Aggregation at High Concentrations in HEK293TCells"
    Marie Saghaeian Jazi, Seyed Mahmoud Arab Najafi
    Iranian Journal of Medical Sciences, Vol. 42, No 1, pp.66-72, 2017
11. "Anticancer Properties of Teucrium persicum in PC-3 Prostate Cancer Cells"
    Majid Tafrihi, Samane Toosi, Tayebeh Minaei, Ahmad Reza Gohari, Vahid Niknam, Seyed Mahmoud Arab Najafi
    Asian Pacific Journal of Cancer Prevention, Vol. 15, No 2, pp.785-791, 2014
12. "Potential role of heat shock proteins in neural differentiation of murine embryonal carcinoma stem cells ( P19 )"
    Elaheh Afzal , Marzieh Ebrahimi , Seyed Mahmoud Arab Najafi, Arezoo Daryadel , Hossein Baharvand
    CELL BIOLOGY INTERNATIONAL, Vol. 35, No 7, pp.713-720, 2011
13. "Regulation of GSK - 3beta and beta - Catenin by Galphaq in HEK293T cells"
    Sara Salmanian , Seyed Mahmoud Arab Najafi, Maryam Rafipour , Maryam Rezae Arjomand , Hamideh Shahheydari , Sara Ansari , Leili Kashkooli , Sj Rasouli , Mariyeh Saghaeyan Jazi , Tayebeh Minaei
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol. 395, No 4, pp.577-582, 2010
14. "Activators of G proteins inhibit GSK - 3beta and stabilize beta - Catenin in Xenopus oocytes"
    Seyed Mahmoud Arab Najafi
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol. 382, No 2, pp.365-369, 2009
15. "Rat marrow - derived mesenchymal stem cell developed in a mediumsupplemented with the autologous versus bovine serum"
    Eslaminejad Mb , Leyla Rouhi , Seyed Mahmoud Arab Najafi, Hossein Baharvand
    CELL BIOLOGY INTERNATIONAL, Vol. 33, No 5, pp.616-607, 2009
16. "Mutations in the beta - catenin gene in gastric and esophageal cancers : an analysis in Iranian patients"
    Seyed Mahmoud Arab Najafi, Roghaye Mohammadzade , Esa Jahanzad , Majid Tafrihi
    Journal of Science University of Tehran, Vol. 4, No 32, pp.167-161, 2007
17. "In vitro differentiation of cord blood unrestricted somatic stem cells expressing dopamine associated genes into neuron - like cells"
    Amir Atashi , Ehsan Arefian , Jafar Kiani , Seyed Mahmoud Arab Najafi, Masoud Soleimani , Mohammad Fallahi Sichani
    CELL BIOLOGY INTERNATIONAL, Vol. 31, No 3, pp.303-299, 2007
18. "Activation of Calcitonin Receptor in HEK-293T Cells Increases the Expression of B-Catenin-target Genes"
    Hadiseh Azadmanesh, Seyed Mahmoud Arab Najafi
    Cells and tissues, Vol. 14, No 3, pp.166-179, 2023
19. "Chloroquine Phosphate Is a Potent Inducer Only in Absence of Glycerol or DMSO to Enter DNA into the HEK293T Cells"
    Sara Ansari, Marie Saghaeian Jazi, Sara Salmanian, Seyed Mahmoud Arab Najafi
    Cells and tissues, Vol. 5, No 2, pp.133-138, 2014
20. "کشت سلولهای بنیادی مزانشیمی موش صحرایی استفاده از پلاسمای تهیه شده از خون محیطی به عنوان مکمل محیط کشت"
    محمدرضا باغبان اسلامی نژاد , لیلا روحی , Seyed Mahmoud Arab Najafi, حسین بهاروند
    فصلنامه خون, Vol. 5, No 1, pp.37-25, 2008

Conference Paper

1. "Identification of a novel protein NNAT, involved in human spermatogenesis and sperm development by multi-omics of single cells and DNA methylation of testicular tissue"
   Seyed danial Hashemi, Seyed Mahmoud Arab Najafi, Maryam Shahhoseini
   Iran's 5th conference on protein and peptide science, 2024
2. "Differential cytoskeleton protein genes expression analysis between human sperm of patients with non-obstructive azoospermia and normal"
   Seyed danial Hashemi, Hossein Azizi, Seyed Mahmoud Arab Najafi
   3rd International Conference on Modern Technologies in Sciences, 2023
3. "Targeted Therapy in Retinoblastoma: Promise and Progress"
   Fatemeh Eslamizadeh, Ehsan Farashahi Yazd, Seyed Mahmoud Arab Najafi
   The First International Congress of Cancer Genomics (CGC2023), 2023
4. "Evaluation of driver mutations in EGFR and KRAS in non-small cell lung cancer and the correlation with program death ligand-1 expression in Iranian patients"
   Zahra Abrehdari-tafreshi, Ehsan Arefian, Seyed Mahmoud Arab Najafi
   CSMBFORUM2023, 2023
5. "The role of Gαq activity on the cellular localization of β-catenin protein: A better understanding of EMT molecular mechanism"
   Ghazal Arjmand Kermani, Seyed Mahmoud Arab Najafi
   5th International and 17th Iranian Genetics Congress, 2023
6. "The effects of Psilocybe cubensis on DNA methylation of some depression related genes in maternal separation stess model in mice"
   Eghbal Jasemi, Seyed Mahmoud Arab Najafi, Ali Razmi
   11th Basic and Clinical Neuroscience Congress, 2023
7. "Targeting Wnt signaling in controlling human cancers"
   Seyed Mahmoud Arab Najafi
   22nd National and 10th international Congress on Biology, 2022
8. "Antibiotics as anti-cancer agents"
   Ghazal Arjmand, Seyed Mahmoud Arab Najafi
   The 5Th INTERNATIONAL CONGRESS ON BIOMEDICINE, 2021
9. "Regulation of β-Catenin signaling by Gq class of G-proteins in colon cancer cells"
   Nasim Forghani, Seyed Mahmoud Arab Najafi
   4th International GI Cancer Congress, 2019
10. "The role of Gαq signaling on β-Catenin expression in HEK293T cells"
    Nahid Khosronezhad, Seyed Mahmoud Arab Najafi
    4th International GI Cancer Congress, 2019
11. "Regulation of wnt signal transduction by hetrotrimeric G-proteins"
    Seyed Mahmoud Arab Najafi
    3rd International Nastaran Cancer Symposium 2017, 2017
12. "The effect of endogenous Gaq activation on expression of some B-catenin target genes in SW480 cells"
    Leyli Naraghi, Nasrin Motamed, Seyed Mahmoud Arab Najafi
    3rd International Gastrointestinal Cancer Congress, 2016
13. "Deregulation of Wnt signal transduction in Human cancer"
    Seyed Mahmoud Arab Najafi
    2nd IASBS Symposium in Biological Sciences: Cancer Cell Biology, 2016
14. "Investigation of Gaq agonists on B-Catenin target gene expression and cellular B-Catenin protein levels in Colon cancer cell line"
    Ashkan Veysi, Eghbal Jasemi, Nazanin Ahmadi, Seyed Mahmoud Arab Najafi
    2nd International and 14th Iranian Genetics Congress, 2016
15. "The Gaq class of Ga proteins positively regulates Wnt/B-Catenin signal transduction"
    Seyed Mahmoud Arab Najafi
    The 2nd International GI Cancer Congress, 2015
16. "The methanolic extract of Teucrium persicum is toxic to cancer cells"
    Majid Tafrihi, Areza Gohari, Seyed Mahmoud Arab Najafi
    1st Tabriz International Life Science conference, 12th Iran Biophysical Chemistry Conference, 2013
17. "The role of two Gq agonists (Thrombin and Carbachol) on cellular b-Catenin protein levels and b-Catenin-target gene expression in HT-29 colon cancer cells"
    Eghbal Jasemi, Mostafa Zamani, Seyed Mahmoud Arab Najafi
    1st Tabriz International Life Science conference, 12th Iran Biophysical Chemistry Conference, 2013
18. "Study on interaction between Gq and B-Catenin signaling pathways in HEK-293T cells"
    Marie Saghaeian, Sedigheh Kolivand, Seyed Mahmoud Arab Najafi
    1st Tabriz International Life Science conference, 12th Iran Biophysical Chemistry Conference, 2013
19. "The cytotoxic effects of methanolic extract of Teucrium persicum"
    مجید تفریحی, احمدرضا گوهری کاخکی , Seyed Mahmoud Arab Najafi
    international congress Natural anticancer drugs, 2012
20. "Investigating the expression of a few B-Catenin target genes in cells treated with Gaq agonists"
    صدیقه کولیوند, مصطفی زمانی, اقبال جاسمی, Seyed Mahmoud Arab Najafi
    12th Iranian Genetic Congress, 2012
21. "The role of herbal extracts on CDh1 (The E-cadherin encoding gene transcription in cancer cells"
    مجید تفریحی, طیبه مینایی , احمدرضا گوهری, Seyed Mahmoud Arab Najafi
    12th Iranian Congress of Biochemistry 4th International Congress of Biochemistry and Molecular Biology, 2011
22. "The role of Gaq agonists on B-catenin expression and function"
    Seyed Mahmoud Arab Najafi, Kolivand Sedigheh
    12th Iranian Congress of Biochemistry 4th International Congress of Biochemistry and Molecular Biology, 2011
23. "Investigation of miRNA-371b-5p expression in serum samples of breast cancer patients"
    فاطمه واعظی, Seyed Mahmoud Arab Najafi, آزاده رخشان, محفوظ قادری, امیر حسین مردی, داور امانی
    23rd National and 11th International Iranian Biology Congress, 2024
24. "The role of paternally expressed gene 6 (PEG6) in recurrent pregnancy loss: A study on gene expression, DNA integrity in spermatozoa and single cell RNA sequencing analysis"
    سید دانیال هاشمی کرویی, Seyed Mahmoud Arab Najafi, مریم شاه حسینی
    23rd National and 11th International Iranian Biology Congress, 2024
25. "Interaction of a novel protein Retrotransposon Gag-like 1 with Protamine 1 involved in human sperm development by multi-omics of single-cell RNA Sequencing and DNA methylation"
    سید دانیال هاشمی کرویی, Seyed Mahmoud Arab Najafi, مریم شاه حسینی
    23rd National and 11th International Iranian Biology Congress, 2024
26. "Bioinformatic analysis of promoter regions of the specific colon tissue genes including CDX2, CLCA1, and MS4A12"
    [] [], Seyed Mahmoud Arab Najafi
    22nd National and 10th international Congress on Biology, 2022
27. "An example for application of minigenes expressing the peptides which regulate cellular signaling pathways"
    [] [], Maryam Rafipour, Seyed Mahmoud Arab Najafi
    12th National And 4th International Biotechnology Congress of Islamic Republic of Iran, 2021
28. "PAR-1 expression in colon cancer cells and the role of PAR-1 activation on B-Catenin expression"
    Elham Ghaed Sharafi, Mojdeh Soori, Mahsa Fanaei, Seyed Mahmoud Arab Najafi
    The 2nd International GI Cancer Congress, 2015
29. "The role of Teucrium persicum extract on cell-cell interactions of PC-3 prostate cancer cells"
    Narges Barati, Majid Tafrihi, Seyed Mahmoud Arab Najafi
    The Third National Seminar on the role of Medical Basic Sciences in Health Promotion, 2015
30. "The role of Teucrium persicum extract on B-Catenin expression in PC-3 prostate cancer cells"
    Narges Barati, Seyed Mahmoud Arab Najafi
    Cancer Congree and Prevention, 2015
31. "The role of heterotrimeric G proteins in the regulation of Wnt/b-Catenin signaling pathway"
    Seyed Mahmoud Arab Najafi
    Shiraz 7th annual colorectal congress, 2013
32. "B-Catenin protein level in HT-29 cells treated with Gaq activators such as Thrombin and Carbachol"
    اقبال جاسمی, مصطفی زمانی, صدیقه کولیوند, Seyed Mahmoud Arab Najafi
    The 17th National & 5th International Iranian Biology Conference, 2012
33. "Cytotoxic Effects of Teucrium persicum extract on cancer cells"
    مجید تفریحی, احمدرضا گوهری, Seyed Mahmoud Arab Najafi
    Th Iranian Biology Conference and the Fifth International Conference, 2012